If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor. Many of these side effects can be managed, and some may go away on their own over time. Contact your doctor if you experience these side effects and they are severe or bothersome.
Your pharmacist may be able to advise you on managing side effects. Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Stop taking the medication and seek immediate medical attention if any of the following occur:. Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health.
These factors may affect how you should use this medication. The Women's Health Initiative WHI study results indicated an increased risk of heart attack, stroke, breast cancer, blood clots in the lungs, and blood clots in the leg veins in postmenopausal women during 5 years of treatment with 0. Other combinations of estrogen and progestins were not studied.
However, until additional data are available, the risks should be assumed to be similar for other hormone replacement products. Allergy: Contact allergy is known to occur with the application of estrogen to the skin. Although it is an extremely rare event, if you develop contact allergy to any component of the medication, you may experience a severe allergic reaction with its continued use.
Blood clotting: This medication can increase the risk of blood clots in the groin, legs or lungs, heart, or brain. If you have or have had a heart attack, a stroke, heart disease, a blood clot in your leg, or have medical conditions that increase your risk of blood clots, you should not use this medication.
Discuss with your doctor whether any special monitoring is needed. The risk is also increased if you are immobilized for prolonged periods and if you are having major surgery.
If possible, this medication should be stopped 4 weeks before major surgery. Talk about the risk of blood clots with your doctor. Blood pressure: This medication can increase blood pressure. If your blood pressure increases while using this medication, contact your doctor. Your doctor will check your blood pressure before you start using this medication and will monitor your blood pressure while you are using this medication.
Bone disease: If you have bone disease due to cancer or a metabolic condition causing too much calcium in your body, you should discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Breast cancer: Studies indicate an increased risk of breast cancer with long-term use of estrogen replacement therapy.
If you have breast nodules, fibrocystic disease, abnormal mammograms, or a strong family history of breast cancer, you should discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Your doctor may suggest that you have a mammogram before starting this medication and at regular intervals while you are using it.
Other known risk factors for the development of breast cancer, such as not having children, obesity, early onset of menstruation, late age at first full-term pregnancy, and late age at menopause, should also be evaluated. If you are taking estrogens, you should have regular breast examinations and should learn how to do breast self-examination. This medication must not be applied to the breasts, as it may have harmful effects on the breast tissue. Dementia: Women over age 65 receiving combined hormone replacement therapy estrogen and progestin may be at increased risk of developing dementia loss of memory and intellectual function.
If you are over 65, talk to your doctor about your concerns. Diabetes: Estrogens may affect blood sugar control. If you have diabetes or are at risk of developing diabetes e. Endometrial cancer: There is evidence from several studies that estrogen replacement therapy can increase the risk of cancer of the endometrium lining of the uterus.
Taking a progestin at the right time along with an estrogen reduces this risk of endometrial cancer to the same level as that of a woman who does not take estrogen. The norethindrone progestin in this medication should counteract the risk of endometrial cancer. If you develop any abnormal vaginal bleeding while using this medication, contact your doctor.
If you have or have had endometrial cancer, you should not use this medication. Fibroids: This medication may worsen fibroids, causing sudden enlargement, pain, or tenderness.
If you notice these effects, contact your doctor. Fluid retention: Estrogen may cause fluid retention and may worsen heart problems, kidney problems, or asthma. If you experience worsening of these conditions while using this medication, contact your doctor. Follow-up examinations: It is important to have a follow-up examination 3 to 6 months after starting this medication to assess your response to treatment. Examinations should be done at least once a year after the first one.
Gallbladder disease: This medication can aggravate gallbladder disease or increase the risk of developing it. If you have gallbladder disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Heart disease and stroke: Studies indicate an increased risk of heart disease and stroke with estrogen with or without progestin for postmenopausal women. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Advanced or acute liver diseases Endometriosis Estrogen dependent tumours Hypersensitivity. Please note that this medicine may be available in various strengths for each active ingredient listed above.
Estradiol: Please consult with your doctor for case-specific recommendations. Norethindrone Acetate: Please consult with your doctor for case-specific recommendations. Estradiol: Please discuss the risks and benefits with your doctor. Norethindrone Acetate: Please discuss the risks and benefits with your doctor.
If you experience drowsiness , dizziness, hypotension or a headache as side-effects when using Estalis 50 MCG PATCH medicine then it may not be safe to drive a vehicle or operate heavy machinery.
One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. Pharmacists also advise patients not to drink alcohol with medicines as alcohol intensifies drowsiness side-effects. Always consult with your doctor for recommendations specific to your body and health conditions.
Most medicines don't come with a potential for addiction or abuse. Usually, the government's categorizes medicines that can be addictive as controlled substances. Please consult the product package to make sure that the medicine does not belong to such special categorizations of medicines. Lastly, do not self-medicate and increase your body's dependence to medicines without the advice of a doctor.
Can i stop using this product immediately or do I have to slowly wean off the use? Some medicines need to be tapered or cannot be stopped immediately because of rebound effects.
Please consult with your doctor for recommendations specific to your body, health and other medications that you may be using. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Those updates may contain important information about the medicine and its use of which you should be aware. All medicines have risks and benefits.
Your doctor has weighed the risks of you using this medicine against the benefits they expect it will provide. Do not use Estalis Continuous or other oestrogens, with or without a progestogen to prevent heart attacks, stroke or dementia.
A study called the Women's Health Initiative indicated increased risk of heart attack, stroke, breast cancer, and blood clots in the legs or lungs in women receiving treatment with a product containing conjugated oestrogens 0. The researchers stopped the study after 5 years when it was determined the risks were greater than the benefits in this group. There are no comparable data currently available for other doses of conjugated oestrogens and MPA or other combinations of oestrogens and progestogens.
Therefore, you should assume the risks will be similar for other medicines containing oestrogen and progestogen combinations. Talk regularly with your doctor about whether you still need treatment with Estalis Continuous. Treatment with oestrogens, with or without progestogens should be used at the lowest effective dose and for the shortest period of time.
Estalis Continuous is a type of treatment called hormone replacement therapy HRT. It is a stick-on patch that contains the hormones, oestradiol and norethisterone acetate NETA. Estalis Continuous is used for the short-term relief of symptoms of the menopause. It can also be used to prevent thinning of the bones in women with a high risk of fractures due to osteoporosis who cannot use other treatments.
Estalis Continuous is used only for women who still have a uterus womb. HRT should not be used for the long-term maintenance of general health or to prevent heart disease or dementia. Oestradiol is a natural female sex hormone called an oestrogen.
It is the same hormone that your ovaries were producing before the menopause. NETA is a hormone called a progestogen. It has effects similar to the female hormone, progesterone, which your ovaries also produced before the menopause.
The menopause occurs naturally in the course of a woman's life, usually between the ages of 45 and After menopause, your body produces much less oestrogen than it did before. This can cause unpleasant symptoms such as a feeling of warmth in the face, neck and chest, "hot flushes" sudden, intense feelings of heat and sweating throughout the body , sleep problems, irritability and depression.
Some women also have problems with dryness of the vagina causing discomfort during or after sex. Oestrogens can be given to reduce or eliminate these symptoms. After the age of 40, and especially after the menopause, some women develop osteoporosis. This is a thinning of the bones that makes them weaker and more likely to break, especially the bones of the spine, hip and wrist.
Exercise, calcium and vitamin D can help reduce the risk of osteoporosis. Women who still have a uterus must take both oestrogen and progestogen as part of HRT. This is because oestrogen stimulates the growth of the lining of the uterus called the endometrium. Before menopause this lining is removed during your period through the action of a natural progestogen. After menopause, taking oestrogen on its own as HRT may lead to irregular bleeding and to a disorder called endometrial hyperplasia.
Progestogens such as NETA help to protect the lining of the uterus from developing this disorder. Estalis Continuous patches release oestradiol and NETA in a continuous and controlled way just as your ovaries were doing before. Because the medicine does not have to pass through your stomach and liver, it allows you to take a much lower dose than would be needed in a tablet and helps to avoid some unpleasant side effects.
Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed it for another purpose. Some of the symptoms of an allergic reaction may include shortness of breath, wheezing or difficulty breathing; swelling of the face, lips, tongue or other parts of the body; rash, itching or hives on the skin.
If you had a severe skin reaction in the past, you could have a very serious reaction if you use any type of oestrogen or progestogen patch, tablet, cream, etc. If you are not sure whether any of the above conditions apply to you, your doctor can advise you. Do not use Estalis Continuous if you are pregnant or breast-feeding.
It may affect your baby. Do not use this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering. In that case, return it to your pharmacist. Tell your doctor if you are likely to have an increased risk of developing blood clots in your blood vessels.
The risk increases as you get older and it may also be increased if:. Tell your doctor if you are taking birth control pills. Estalis Continuous is not a contraceptive. Since pregnancy may be possible early in the menopause while you are still having menstrual periods, you should ask your doctor to suggest another non-hormonal method of birth control. Tell your doctor or pharmacist if you are taking any other medicines, including medicines that you buy without a prescription from a pharmacy, supermarket or health food shop.
You may need to take different amounts of your medicines or to take different medicines while you are using Estalis Continuous.
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